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Green Tea In Diet Improves Endocrine Stem Cell Line


Green tea has been reported to possess antioxidant, antitumorigenic, and antibacterial qualities that regulate the endocrine system. Previous epidemiological studies found that the bone mineral density (BMD) of postmenopausal women with a habit of tea drinking was higher than that of women without habitual tea consumption. However, the effects of green tea catechins on osteogenic function have rarely been investigated.

In a murine bone marrow mesenchymal stem cell line, D1, the mRNA expressions of core binding factors a1 osterix, osteocalcin, ALP increased after treatment. These results demonstrated that long-term treatment of EGCG increases the expressions of osteogenic genes, elevates ALP activity and eventually stimulates mineralization, in spite of its inhibitory effect on proliferation. This finding suggests that the stimulatory effects of EGCG on osteogenesis of mesenchymal stem cells may be one of the mechanisms that allow tea drinkers to possess higher BMD.

Implementing green tea into a diet can improve one’s health on a cellular level.

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